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This equalises vial pressure and prevents vacuum formation, which can pull contaminants through the stopper seal during storage

According to our chemical analyses, the CHCl 3 fraction contains alkaloids, triterpenes and 7-deoxyloganic acid, the latter also found in the BuOH fraction, along with antioxidant substances such as phenolic glycosides and anthocyanidins

doi: 10.2337/db19-0153 43 KalagiN

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The lines are not-coincident, but parallel