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HuCCT1 (1 10 4 cells) were suspended in 400 l Cellmatrix type IA collagen solution in a 48-well plate and were allowed to gel for 60 min at 37 C

Mariani J, Coppola G, Zhang P, Abyzov A, Provini L, Tomasini L, et al

Cancer can cause multiple changes in the genetic expression via DNA hypermethylation and hypomethylation, loss of genomes responsible for DNA methylation, modifications in histone, and modifications in miRNA expression, which invariably control genetic expressions [97,98,99]

doi: 10.3389/fncel.2019.00299

After the experiment, all the murine models were histologically examined, and it was determined that the murine models with BPC-157 exhibited a prominently higher number of collagen and blood vessels formed as compared to the placebo murine models

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