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Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug

Currently NAC has the most evidence of having a beneficial effect as an adjuvant agent in the negative symptoms of schizophrenia, severe autism, depression, and obsessive compulsive and related disorders

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Meta analyses did not find any significant effects with melatonin on insomnia disorder (75) , secondary sleep disorders associated with medical, neurological, or substance abuse disorders (5) , or on sleep quality in menopausal women (71) , but supplementation improved subjective sleep quality in patients with traumatic brain injury (44) and Parkinsons disease (76) , and cognitive outcomes in patients with Alzheimers disease (72)

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