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In the specific context of hearing and tinnitus, a conceptual link exists in the proposed brain-ear-heart axis, where neurotrophic factor supplementation to the cochlea could inhibit pathological protein aggregation and support neuronal health, potentially preventing conditions like AD and associated amyloid cardiomyopathy (Shityakov et al., 2021)

Further research is required to shed light onto BBB alterations as a pathogenic mechanism in PD

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NAD+ injections help counteract these effects by promoting cellular repair and improving skin elasticity

doi: 10.1080/003655200750024560