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They reduce appetite from different receptor systems, which is precisely why an amylin analog is studied alongside a GLP-1 analog in CagriSema rather than as a substitute for one

10.1016/j.jconrel.2024.01.019 J

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Compounding these clinical challenges is a significant translational barrier: current mechanistic studies rely heavily on commercialized cell lines and rodent models

Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, DAmico D, et al

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