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Degenerated menisci produce catabolic mediators such as prostaglandin E2 (PGE2), nitric oxide, and cytokines that can diffuse into synovial fluid and exacerbate articular cartilage degeneration (Krupkova et al., 2018)

rxlist.com (Miochol ) Keywords Norepinephrine Trade Name: Levophed Drug Class: Catecholamine, Sympathomimetic Mechanism of Action: Functions as a peripheral vasoconstrictor (by stimulating 1 and 2 adrenergic receptors ) and as an inotropic stimulator of the heart (by stimulating 1 adrenergic receptors ) When given i.v

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