Spermidine increased levels of LC3-II, TFEP and p62, which are important components of autophagy (Reference Omar, Omar and Shoela81)
Reduce or hold the dose if flushing, nausea or other GI effects occur
Lenny Macrina: Yeah, I will definitely
Formulation matters a lot: Copper peptides become inactive in the presence of strong chelating agents or low-pH acids
doi:10.1002/mc.20741, PMID: 21319226 Yue P, Zhou Z, Khuri FR, Sun SY (2006) Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me)
BPC-157 ("Body Protection Compound 157") is a synthetic pentadecapeptide a 15-amino-acid sequence originally isolated as a fragment of a protein found in gastric juice