When interpreted together with the findings of the STEP 4 withdrawal trial and STEP 1 off-treatment extension study, which both showed weight regain after semaglutide discontinuation (after 20 weeks treatment in STEP 4 and 68 weeks treatment in STEP 1) 23,24 , these results support the benefit of continued semaglutide treatment for sustained weight loss
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As levels rise, these symptoms can improve within a few days or weeks
For individuals experiencing chronic fatigue or low energy, evaluating B12 deficiency can be a crucial step
(PubMed) Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM
Potential Side Effects Reported side effects may include: Injection site pain, redness, or irritation Mild diarrhea Itching or rash Headache, dizziness, and nausea Acneiform skin eruptions Hypokalemia (low potassium) see Warnings above Serious adverse reactions are uncommon but may occur
