(2000), Horm Res 53(Suppl 3), PubMed 10971106 Statistics from preclinical literature AOD-9604 = modified fragment of hGH 177191 + N-terminal Tyr (sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe), molecular weight 1815.1 Da Developed at Metabolic Pharmaceuticals (Australia) based on the work of professor Frank Ng (Monash University) in the 1990s Standard experimental dose in obesity clinical trials: 1 mg/day subcutaneously (Phase 2b, Heffernan et al.) Mechanism: stimulation of 3-adrenergic receptors in adipose tissue, increased lipolysis and fatty acid oxidation without activation of the hGH receptor (no IGF-1 increase) Phase 2b clinical trial (2007, 300 patients): weight reduction ~2.8 kg vs placebo over 12 weeks FDA status: NDI rejection (2014) as a dietary supplement
Angew Chem Int Ed 60(5):22212231 Liu Y et al (2021) Immobilization strategies for enhancing sensitivity of electrochemical aptamer-based sensors
Thus, it may improve your insulin sensitivity and glucose metabolism
Glutathione transferase (GST)-activated prodrugs
Gold KA, Lee JJ, Ping Y, Behrens C, Liu D, Lee HY, Koo JS, Lotan R Solis L, Rinsurongkawong W, Stewart DJ, Hofstetter WL, Swisher SG , Lippman SM, Wistuba II, Hong WK, Kim ES
It helps in reducing Acne and dark spots
