Rommens JM, Iannuzzi MC, Kerem B, Drumm ML, Melmer G, Dean M, Rozmahel R, Cole JL, Kennedy D, Hidaka N, et al
This depends on your personal situation, how low your vitamin B12 levels are intracellularly, what kind of medical conditions you have, and how much improvement you get from the B12 shots
relevance to humans not established, but contraindicated in those with MTC/MEN2 history
Standard Research Protocol Dose: 300 mcg per day subcutaneous injection Timing: Morning, fasted state (at least 30 minutes before food or exercise for maximal absorption) Cycle length: Typically 8 to 12 weeks on, followed by a 4-week rest period Reconstitution: Standard BAC water reconstitution
1.5-2mg : Noticeable appetite reduction, early fat loss visible on the scale
Annual testing is probably sufficient for most users