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For the purposes of testing drug-specific associations, we repeated the GWAS procedure for the semaglutide and tirzepatide-treated populations separately, removing the drug-type covariate and interaction terms as appropriate

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This process involves the combination of two molecules or molecular fragments to form a higher-order structure via non-covalent interactions or covalent bonds, enabling the rapid construction of complex molecular architectures with diverse physiological properties 3,4

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