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Inflammation and cancer progression have been associated with the Toll-like receptor 4 (TLR4) signaling pathway (89)

Reparon-Schuijt, C

The lowered or nonexistent HO-1 expression within macrophages is linked to an increase in pro-inflammatory cytokine expression, namely monocyte chemotactic protein 1 (MCP-1) and IL-6

Maiti A, Kantarjian HM, Popat V, Garcia-Manero G, Konopleva M, Verstovsek S, Andreeff M, Borthakur G , Kadia T, Daver N, Pemmaraju N, DiNardo CD, Pierce S, Wierda WG, Kornblau S, Ravandi F, Cortes JE

The idea is not that DSIP replaces opioids, but that it might support the body during the withdrawal phase

Store in a cool, dry place away from direct sunlight.