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Symptoms are typically mild and mouth-localized

Alzheimers Res Ther , 2017, 9(1): 62-72

FIGURE 3 Examining the zeta potential changes, Figure 3B illustrates that GO@GSH-FA nanoparticles exhibited a marked increase in zeta potential over time in both 0.5 mM and 5 mM H 2 O 2 environments, indicating the oxidative degradation of the nanoparticles

By lowering GSH levels, p53 increases the cellular vulnerability to oxidative stress and ferroptosis (129)

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Exposure to environmental toxins such as heavy metals (e.g., cadmium, lead) and endocrine-disrupting chemicals (e.g., bisphenol A, phthalates) can increase ROS production in spermatozoa