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455 Ferroptosis in Duchenne muscular dystrophy Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by mutations in dystrophin protein encoded by the DMD gene

Subsequently, cAMP phosphorylates protein kinase A (PKA), which in turn phosphorylates other regulatory proteins involved in airway smooth muscle spasm, regulation of intracellular calcium, and bronchodilation

Natural compounds such as resveratrol and berberine have demonstrated the ability to modulate GSK-3 activity, thereby reducing tau pathology (Wang M

Approved in 1997, withdrawn in 2008 for commercial (not safety/efficacy) reasons

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