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76 Other compounds, such as pantetheine, which also includes sulfhydryls, are under investigation as anticataractogenic agents

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Kumar, R

Interestingly, both in vivo and in vitro studies have shown that the accumulation of -syn in the mitochondria of human DA neurons leads to decreased complex I activity, increased production of ROS, reduced substrate-specific respiration, and increased mitophagy [86, 87]