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Rapid weight loss may lead to Ozempic face, which is a non-medical term referencing a sagging and aged appearance that occurs due to rapid weight loss, which also affects facial volume and muscle mass

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doi: 10.3389/fcell.2021.683609 Received 21 March 2021 Accepted 30 April 2021 Published 09 June 2021 Volume 9 - 2021 Edited by Jiri Novotny, Charles University, Czechia Reviewed by Flavio Maina, Aix-Marseille Universit, France

Insulin-like Growth Factor-1 (IGF-1) is a naturally occurring polypeptide hormone consisting of 70 amino acids and plays a central role in cellular growth signalling, metabolic regulation, and tissue development pathways