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Human research is limited, though animal data is robust and consistent across multiple models
These studies aim to map potential mechanisms rather than confirm therapeutic outcomes
The input variables considered, obtained from a systematic review of the literature and data of the 1997 Nationwide Inpatient Sample, were: the estimated mortality rate after elective laparoscopic (1.4%, range 0%-5.2%) and emergency (5.4%) PEH repair, the annual probability of developing symptoms progression (13.8% range 8.1%-21.7%), the annual probability of acute presentation requiring emergency surgery of untreated patients (1.1% range 0.7%-1.9%), and the annual probability of HH recurrence after surgical repair (1.9% range 0.3%-5.4%)
doi: 10.1016/j.reumae.2011.09.003
Peptides are short chains of amino acids, the same building blocks that make up proteins
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