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Intravenous administration without an isotonic admixture can cause hemolysis (red blood cell destruction)

Early diagnosis improves outcomes, so persistent or progressive symptoms should lead to a timely clinical assessment, often involving imaging and specialist referral

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doi: 10.1093/bioinformatics/btp324, 63 LiH.HandsakerB.WysokerA.FennellT.RuanJ.HomerN.et al

removing vials from the carton and storing them on an open shelf under fluorescent or natural light is a documented degradation accelerant