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Lee, J.D., Nunes, E.V., Novo, P., et al

These local reactions typically resolve quickly and diminish with continued use as technique improves

Cancer Cell 26 , 248261 (2014)

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The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease

Specifically, the peptide downregulates inflammatory genes including interleukin-1, tumor necrosis factor-, and nuclear factor-B, while upregulating protective genes such as those encoding antioxidant enzymes, DNA repair proteins, and extracellular matrix components