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The regulatory asymmetry between topical and injectable in the 503A list reflects, in part, that asymmetry in the evidence

0.25mg dose: Draw to 10 units 0.5mg dose: Draw to 20 units 1.0mg dose: Draw to 40 units 1.7mg dose: Draw to 68 units 2.0mg dose: Draw to 80 units 2.4mg dose: Draw to 96 units Notice how each dose falls on a round number