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Chowdhry S, Zhang Y, McMahon M, Sutherland C, Cuadrado A, Hayes JD

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Severe neurologic impairment Difficult to control seizures Motor and cognitive impairments Cerebral palsy Cerebral edema Can lead to death

Highlights: Blocks interaction between FOXO4 and p53 to induce senescent-cell apoptosis

Group and Peer Support Depression can make life feel isolating, but connecting with others can shift everything

Immunotherapy (treatment that helps the body's own immune system fight cancer) with checkpoint inhibitors (such as nivolumab or pembrolizumab), which has improved outcomes in advanced melanoma over the past decade