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The bead-bound cells are separated from unbound cells using a magnetic cell sorter

Univariate statistical testing using two-sample t-tests with confirmation by Wilcoxon rank-sum tests identified four metabolitescoumarin, L-leucine, L-octanoylcarnitine, and kaempferolthat differed significantly between ASD and control groups after FDR correction, with large effect sizes (Supplementary Table S2)

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However, VEGF pathway activation in the context of normal tissue repair differs substantially from VEGF activity in established tumors

By stabilizing the mast cell's internal environment, glutathione helps to raise the threshold for activation, making the cells less likely to misfire in response to everyday triggers

doi: 10.1017/neu.2013.35