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Tranexamic acid is an underdog additive that targets dark spots, hyperpigmentation, and melasma all at once without irritating sensitive skin in the processin fact, it's one of the few discoloration-diminishing ingredients that can be mixed with other skin brighteners like retinol and hydroquinone

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The use of antioxidant supplements or cholesterol-lowering agents

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Important distinction: DAO support may help with histamine from food, but it does not necessarily correct intracellular histamine metabolism, high whole-blood histamine or an undermethylated mood pattern