Anyone can be affected, but some groups are more at risk: Vegetarians and vegans, since B12 mainly comes from animal products Older adults, as absorption gets harder with age People with digestive issues like Crohns or coeliac disease Those taking certain medications, such as long-term metformin or stomach acid reducers People with pernicious anaemia, an autoimmune condition that stops you from absorbing B12 If you fit into one of these categories and notice symptoms, its worth getting your levels checked
The question is whether adding anything to it provides meaningful benefit
Regulatory Evidence No current UK marketing authorisation was identified in the official sources reviewed
10.1038/s41572-020-0187-8 [DOI] [PubMed] 55.Vidal-Alaball J, Butler CC, Potter CC (2006) Comparing costs of intramuscular and oral vitamin B12 administration in primary care: a cost-minimization analysis
[3] In REDEFINE 2 , a parallel 68-week Phase 3a trial in 1,206 adults who had overweight or obesity and type 2 diabetes, once-weekly CagriSema produced an estimated mean weight change of 13.7% versus 3.4% with placebo, alongside marked improvements in glycemic control
Where a patient is interested in peri-operative regenerative strategies and where it is clinically appropriate, that conversation happens in detail at the consultation, with a full review of evidence, regulatory status, alternatives, and what is or is not available through proper medical channels
