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ELIMINATION RATE CONSTANT AND ELIMINATION HALF-LIFE The rate of elimination for most drugs is a first order process

4.5.2 The role of the System X c - GSH-GPX4 axis in the progression of kidney cancer The System X c - transports extracellular cystine into the cell and transports intracellular glutamate out of the cell to further GSH

Neurotherapeutics 16, 649665

You can only eat so much food in one day and sometimes B12-rich foods arent abundant

This is not a speculative concern it is precisely why parenteral nutrition copper dosing is an order of magnitude lower than oral intake, at 0.30.5 mg/day, and why the dose is reduced, with monitoring of serum concentrations, in cholestasis where biliary excretion is impaired