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Main pathway: G-actin sequestration Native T4 binds monomeric G-actin with a dissociation constant (KD) of approximately 1 M, controlling the pool of free actin available for polymerization into F-actin (actin filaments)

2006;136(6 Suppl):1652S9S

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Researchers may use the peptide in cell culture experiments, vascular biology studies, and preclinical research models that explore how cells respond to signaling molecules during tissue stress or repair

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The advantage of on-column tag removal is that it eliminates the extra step of separating the cleaved protein from GST, since the GST-tag itself remains bound to the medium