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PMID: 27467578

Besides, nanotechnology has been applied to prepare curcumin nano preparations with higher solubility and slower biotransformation rate, thereby enhancing its bioavailability

Antioxidant enzymes Antioxidant enzymes are a class of proteins/metalloproteins, that catalyze the transformation of ROS and/or their byproducts into more stable, usually less harmful species

Unlike kinases where multiple inhibitors have been developed and tested in clinical trials the most commonly used palmitoylation inhibitor 2-BP cannot be used in the clinic due to its toxicity with off-target effects including interference with fatty acid metabolism (209)

10.1074/jbc.M203009200 J

Histopathological evaluation used a modified Mankin scoring system