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Similarly, targeting NRF2 to upregulate phosphorylase kinase catalytic subunit 2 promotes ferritinophagy and mitochondrial stress-dependent ferroptosis, increasing radiosensitivity (123)

The compound described is not approved for human therapeutic use absent a controlled clinical trial

Cancer stem cells (CSCs) are a subpopulation within solid tumors that exhibit resistance to conventional chemotherapy

Mass spectrometry (MS) is used for molecular identity confirmation

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