Development of a Sexually Differentiated Behavior and its Underlying CNS Arousal Functions
Insert the needle quickly and decisively at a 90-degree angle into pinched skinhesitation or slow needle entry increases tissue trauma
Molecular biology workflows that track changes in protein signaling or other biomarker outputs following peptide exposure (study-specific)
Not a peptide technically, but grouped here because we dose it alongside peptide protocols
In this study, we used cryogenic electron microscopy (cryo-EM) to determine structures of Cagri bound to Gs-coupled, active, AMY 1 R, AMY 2 R, AMY 3 R and CTR and compared the mode of interaction of Cagri and the associated dynamics of the Cagri-bound receptor complexes with previously reported cryo-EM structures and dynamics of receptors bound to rat amylin (rAmy, all receptor subtypes), sCT (CTR, AMY 1 R, AMY 2 R) 15 or recently developed amylin-based peptides (CTR and/or AMY 3 R) 16
Lancet 406 , 149162 (2025)