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However, this becomes dysfunctional in AD, further worsening the effects of oxidative stress ( 3.3 Parkinsons disease PD is a neurodegenerative disorder that typically presents later in life with generalized bradykinesia and another symptom of resting tremor or rigidity

Mechanisms of cell death in oxidative stress

10.1007/s11103-013-0136-y 101 Magnin-RobertM.AdrianM.TrouvelotS.SpagnoloA.JacquensL.LetouseyP.et al

doi:10.1042/0264-6021:3600001

The first incorporates GSH into the mitochondria by inorganic phosphate exchange and the second by exchange of 2-oxoglutarate (Figures 2, 4)

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