Comparative studies involving repairassociated peptides in preclinical systems
( ( ( ( ( ( After review of the information provided by the applicant, we have the following concerns regarding whether NexoBrid TM meets the substantial clinical improvement criterion
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Dynamic proctography is indi- cated for fecal incontinence when clinical features suggest excessive perineal descent, a clinically significant rectocele (eg, in patients who splint the vagina to facilitate rectal emptying), an enterocele, or internal rectal intussusception
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