Among natural antioxidants, in LPS-stimulated RAW264.7 macrophages, apigenin has been shown to suppresses the expression of COX-2, iNOS, as well as the inhibition of the MAPK signaling pathway and in IgE-sensitized RBL-2H3 cells, it suppresses of the FcRI signaling pathway, suggesting potential anti-allergic and anti-inflammatory activities (Park C.-H
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W.LonzarichL.HatiS.et al
J Invest Dermatol Symp Proc 6(3):170174
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Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice (in Eng)