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For example, a ferroptosis-prone chondrocyte cluster with high expression of ACSL4 and Tf, but low expression of FTH1 and TRPV1, has been identified in severely degenerated cartilage regions ( We propose that selectively targeting ferroptosis in specific cell populations may enhance therapeutic precision

SY: Conceptualization, Funding acquisition, Methodology, Writing review & editing

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The used term chronic diabetic complications is misleading for both doctors and patients, leading to the blood glucose-focused management, while ignoring the development of TOD related to other metabolic disorders in the MDS

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