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Cell Death & Disease, 13 (4), 1-9

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If applied locally via injection, as was done in the study, there is also a risk of structural damage as the needle could break the fragile external walls that protect the discs

Completing your prescribed cumulative dose is recommended even if your skin shows initial signs of improvement

Actionable Takeaway When appropriate, counsel patients to incorporate regular sauna bathing as a longevity and cardiovascular riskreduction modality (e.g., ~4 sessions/week, 1520 minutes at typical Finnish sauna temperatures), after screening for contraindications such as unstable cardiovascular disease, hypotension, dehydration, pregnancy, or heat intolerance

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