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Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements
Additionally, it has shown potential neuroprotective and cardioprotective activities in various experimental models, making it a widely explored peptide in tissue repair and regenerative medicine research
[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Hou X, Du Q, Li R, Zhou M, Wang H, Wang L, et al
NMR Structural Resolution of FOXO4-DRI/p53TAD2 Complex (Nature Communications, 2025) Disordered-to-Ordered Complex Formation: Structural Basis of FOXO4-DRIs Senolytic Mechanism A landmark structural study published in Nature Communications (2025) resolved the solution NMR structural models of the p53 transactivation domain (TAD2) in complex with the FOXO4 forkhead domain and with FOXO4-DRI
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T., Wang, C
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