Patients on long-term GLP-1 therapy with restricted diets should have B12 monitored
This method bypasses the digestive system, making it ideal for people who: Have trouble absorbing B12 due to gastrointestinal issues (like Crohns disease or coeliac disease) Are on medications that interfere with B12 absorption (like metformin or anti-acids) Follow vegan or vegetarian diets Have undergone gastric surgery
Sites Abdomen (2 from navel) Thighs/arms Rotate to avoid irritation Needles 29-31G insulin syringes 0.5-1 mL, length Reconstitution (10 mg Vial) Add 2 mL bacteriostatic water (0.9% benzyl alcohol)
This makes it useful for individuals who want fat-loss support without feeling flat, depleted, or overly reliant on stimulant-based products
Medications that reduce absorption of B12 metformin (for diabetes) and antacids (that reduce the amount of stomach acid) are the main ones
For the initial reconstitution process (adding the water), a larger 3mL syringe with a separate needle is more practical