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The liberated Nrf2 then translocated into the nucleus

Glutathione plays a crucial role in detoxification and immune function

The components of this chain are each supported in the literature: oxidative stress and protease exposure impair mitochondrial function and cause DNA fragmentation in ovarian somatic cells, and disturbed FF redox balance correlates with altered steroidogenic gene expression and poorer oocyte competence [60]

PMID: 19464452

Jarrott et al., 2022)

Secondary plots for the rate constants of the rapid first reaction phase at variable PfGrx concentrations deviated from linearity and showed a hyperbolic correlation at millimolar GSH concentrations (Fig