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Preclinical and early human research suggests its role in promoting longevity, regulating circadian rhythms, and supporting cellular repair processes, making it of great interest to researchers in gerontology, oncology, and molecular biology

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Four -ketoacid dehydrogenase complexes ( Figure 4 ), including: (i) the pyruvate dehydrogenase complex that catalyzes the conversion of pyruvate to acetyl-coenzyme A (CoA), an important substrate for energy production via the citric acid cycle

To the contrary, high to normal levels of circulating IGF-1 correlate with a rise in adiponectin levels and a reduced prevalence of MetS is found [233]

Yes, and they should be