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These antioxidants act through direct and indirect mechanisms, offering broad and multifaceted protection to cells [36]

doi: 10.1016/j.btre.2018.e00247

In some embodiments, the otic pharmaceutical formulation comprises between about 75% to about 95% by weight of the triglycerides

Glossary 2-AR 2-adrenoceptor DAMGO [D-Ala 2 , N -MePhe 4 ,Gly-ol 5 ]enkephalin FRET Fluorescence Resonance Energy Transfer GPCR G protein-coupled receptor GRK G protein-coupled receptor kinase MOPr -opioid receptor PKA protein kinase A PKC protein kinase C Footnotes Conflict of interest The authors state no conflict of interest

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Xiahou et al., 2017)