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i , Immunoblot of indicated proteins in HEK-293T cells expressing an SLC25A40 cDNA in the presence or absence of BSO

Hydrogen sulfide (HS) is predominantly produced enzymatically through the activity of cystathionine -synthase (CBS), cystathionine -lyase (CTH), 3-mercaptopyruvate sulfurtransferase (MPST) and the methanethiol oxidase selenium-binding protein 1 (SELENBP1) 3,4,5,6

As an antioxidant, glutathione is great at fighting off harmful elements in our skin, which helps reduce dark spots and evens out skin tone

TNF-, tumor necrosis factor-alpha

doi:10.1016/j.jaad.2016.04.051

A similar result was reported by Wang et al