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It is used to treat and prevent vitamin B6 deficieny resulting from poor diet, certain medications, and some medical conditions

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Persistent DNA damage leads to the formation of chromatin-modifying segments known as DNA segments with chromatin alterations reinforcing senescence (DNA-SCARS) [18]

Nausea, vomiting, diarrhea, constipation, and abdominal pain were mainly transient and mild to moderate

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Furthermore, studies on serum from SZ patients showed elevated levels of polyamine oxidase (the enzyme responsible for degrading PAs) (96, 97), while the activities of three enzymes involved in PA synthesisornithine aminotransferase, antizyme inhibitor 1 (AZIN1), and ornithine cyclodeaminase were found to be reduced in the prefrontal cortex of both treated and untreated patients (98), ultimately potentially leading to disrupted polyamine homeostasis