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Gene expression and phosphorylation of AANAT (the rate-limiting enzyme in melatonin synthesis) become downregulated

Depending on the availability of cellular GSH and the activation of glutathione S-transferase subclasses, detoxification of AFB1 is facilitated [24]

[3] The GLP-1 and GIP arms deliver the incretin effects now familiar from drugs like semaglutide and tirzepatide appetite suppression, slowed gastric emptying, and improved glucose handling

EMBO J 5:12211227 Brigelius-Floh R, Maiorino M (2013) Glutathione peroxidases

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