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This novel small molecule has been explored in exercise mimetic research, with preclinical studies investigating its effects on mitochondrial biogenesis, endurance capacity, and metabolic gene expression

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251,252,253 Thus, NAD(P) + /NAD(P)H acts as an important modulator of cellular energetic status, enabling the reset of redox rhythmic and transcriptional oscillations based on metabolic signals

Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis

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Melnyk et al