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Note that sonication can cause solution warming and potential degradation

The concerns that arose in the meta-analysis caused a desire to study this topic deeper, she says, adding that the Food and Drug Administration (FDA) is currently investigating several safety concerns with semaglutide and has added blood clots to the investigation

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Dosage may be reduced to 0.5 mL weekly in patients experiencing gastrointestinal intolerance or increased to a maximum of 2 mL twice weekly for short-term metabolic intensification when supervised by a qualified clinician

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The FDA isn't required to follow the group's advice, though it usually does