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Ferroptosis, an iron-dependent programmed cell death characterized by uncontrolled lipid peroxidation, involves GSH depletion and GPX4 inactivation (Ursini and Maiorino 2020), leading to lethal accumulation of lipid peroxides that disrupt cellular membranes (Yang et al

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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1871:119823