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Histological analysis reveals that aged kidneys accumulate senescent cells primarily in tubular regions, identified by loss of Lamin B1 (LMNB1), elevated senescence-associated -galactosidase activity, and expression of inflammatory IL-6

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However, the above-mentioned increase in pro-inflammatory cytokine and chemokine RNA expression was significantly suppressed in the Si-DSS group (Fig

Xie Y, Bergstrm T, Jiang Y, Johansson P, Marinescu VD, Lindberg N, et al