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22.1%) included patients with a high prevalence of recurrent ICH (8.8%), associated subarachnoid hemorrhage (92.0%) and finger-like projections (54.1%), suggesting a cerebral amyloid angiopathy (CAA)-like profile

Open-label clinical trials have shown that rhGH treatment in children with PMS raised serum IGF-1 levels by at least 2 SD from baseline without serious adverse events and produced effects similar to rhIGF-1 on social isolation and other central manifestations of PMS syndrome (149, 150)

This cellular energy crisis directly manifests as the profound physical fatigue, "brain fog," and post-exertional malaise (PEM) that patients experience

Aggressive agitation breaks peptide bonds

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