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As a result, GSH is involved in a number of key detoxification reactions and has a high capacity for preventing oxidative stress-induced cellular damage

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This NAD+ elevation activates sirtuins, particularly SIRT1 in adipocytes and hepatocytes, which deacetylates and activates numerous metabolic regulatory proteins including PGC-1, a master regulator of mitochondrial biogenesis, oxidative metabolism, and thermogenesis

(2012) found that CBD (1 M) administered to inflammatory-induced primary oligodendrocyte cell cultures from the cortex of 2-day-old rats protected OPCs from oxidative stress and apoptosis

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(2008) 294:L111926