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Thus, omega-3 PUFA-derived SPMs effectively balance the neuroinflammatory and pain processes in the interaction between glial cells and neurons (18)

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Toll-like receptor misrecognition is considered to be an important step in alpha-synucleinopathy progression, and increased intestinal permeability, immune activation, and enteric neuroglial activation are keys in the pathophysiology of Parkinsons disease (158)

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