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In the present study, PFOS time dependently increased IRE1 (an ER stress marker) expression, indicating ER stress induction, which could be eliminated by l-Carnitine through its antioxidative activity

Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis

Glutamine metabolism and cancer-associated fibroblasts(CAFs) CAFs represent a pivotal element of the TME, exerting a pivotal function in shaping the TME

It is important to acknowledge this gap explicitly: numerous promising agents have not yet been tested in large, high-quality trials, or have only small studies with inconclusive results

Cochran et al., 2015

Di Marzio L, Moretti S, D'Alo S, et al